National Department of Health Provides Update on Mpox
SATSA is sharing the latest update from the National Department of Health on Mpox (formerly known as monkeypox), following a rise in confirmed cases in South Africa. This update is shared proactively, in the interest of providing accurate, fact-based information to our trade partners and the travelling public.
What the Department of Health Has Reported
As of 18 September 2026, the Department has confirmed 19 laboratory-confirmed Mpox cases nationally:
- 15 in the Western Cape (Cape Town)
- 3 in Gauteng
- 1 in KwaZulu-Natal
Thirteen of these cases were recorded between 13 August and 17 September, which the Department says points to rapid local transmission. Cases range in age from 23 to 50, and the majority are male. One recent case involves a person who had travelled to Spain and returned to South Africa on 14 September; South African authorities are liaising with Spanish counterparts to confirm this case.
The Department has emphasised early detection, surveillance and public cooperation as key to containing spread, and has secured a limited supply of Mpox vaccine (Tecovirimat) for targeted use in outbreak response.
Frequently Asked Questions
What is Mpox and how does it spread?
Mpox is a viral illness. It spreads mainly through skin-to-skin contact with an infected person's rash or sores, through contact with contaminated items like bedding or clothing, and less commonly through prolonged close face-to-face contact.
What are the symptoms?
Fever, headache, muscle aches, fatigue, and a rash or skin lesions on the face, hands, feet or other body parts. Symptoms typically appear 6 to 13 days after exposure, though this can range from 5 to 21 days.
What preventative measures can be taken?
Frequent hand washing or use of sanitiser is one of the most effective preventative measures. Avoiding close physical contact with anyone showing symptoms, and avoiding shared use of bedding, clothing or towels with an infected or symptomatic person, also reduces risk. Good hygiene practices around coughing and sneezing further help limit transmission.
What should someone do if they feel unwell and suspect they may have symptoms?
Anyone experiencing symptoms such as fever, fatigue, or a rash or skin lesions, particularly if they have had close contact with a confirmed or suspected case, should seek medical attention immediately. They should avoid close contact with others and, where possible, isolate themselves until they have been assessed. This applies regardless of travel history.
Are there vaccines available?
The Department has secured a limited supply for targeted outbreak response. This is not a general travel vaccination requirement.
Credible Sources to Monitor
For the latest information, we encourage readers to refer directly to the following official sources:
- National Institute for Communicable Diseases (NICD): nicd.ac.za
- National Department of Health: health.gov.za
- Africa CDC: africacdc.org
SATSA will continue to monitor this situation and will provide updates should there be any material change.







